Histamine is the main natural chemical responsible for true allergic reactions, so the symptoms produced are almost identical to a food allergy. Histamine is not destroyed by normal cooking temperatures, so even properly cooked fish can still result in poisoning. At temperatures above 16 ☌ (60 ☏), histidine is converted to the biogenic amine histamine via the enzyme histidine decarboxylase produced by symbiotic bacteria such as Morganella morganii (this is one reason why fish should be stored in the freezer). Histidine is an amino acid that exists naturally in many types of food, including fish. Unlike many types of food poisoning, scombroid form is not brought about by ingestion of a pathogen. In rare cases, the poisoning may result in death. In the worst cases, the poisoning may cause: edema (generalized if it occurs at all).torso or body rash: The rash associated with scombroid poisoning is a form of urticaria, but most commonly does not include wheals (patchy areas of skin-swelling also known as hives) that may be seen in true allergies.facial rash (intense itching may accompany the rash).burning-peppery taste sensations in the mouth and throat.The first signs of poisoning suggest an allergic reaction with these symptoms: They usually last for about 10 to 14 hours, and rarely exceed one to two days. However, symptoms may show over two hours after eating a spoiled dish. People with asthma are more vulnerable to respiratory problems such as wheezing or bronchospasms. Symptoms typically occur within 10–30 minutes of ingesting the fish and generally are self-limited. The condition was first described in 1799. It occurs globally in both temperate and tropical waters. Along with ciguatera fish poisoning, it is one of the most common type of seafood poisoning. Epinephrine may be used for severe symptoms. Treatment is generally with antihistamines such as diphenhydramine and ranitidine. Prevention is by refrigerating or freezing fish right after it is caught. If a number of people who eat the same fish develop symptoms, the diagnosis is more likely. Diagnosis is typically based on the symptoms and may be supported by a normal blood tryptase. Subsequent cooking, smoking, or freezing does not eliminate the histamine. These fish naturally have high levels of histidine, which is converted to histamine when bacterial growth occurs during improper storage. Fish commonly implicated include tuna, mackerel, mahi mahi, walu walu, sardine, anchovy, bonito, herring, bluefish, amberjack, and marlin. Scombroid occurs from eating fish high in histamine due to inappropriate storage or processing. Rarely, breathing problems, difficulty swallowing, redness of the mouth, or an irregular heartbeat may occur. Onset of symptoms is typically 10 to 60 minutes after eating and can last for up to two days. Symptoms may include flushed skin, sweating, headache, itchiness, blurred vision, abdominal cramps and diarrhea. Scombroid food poisoning, also known as simply scombroid, is a foodborne illness that typically results from eating spoiled fish. Typically based on symptoms, blood tryptase Tuna, mackerel, mahi mahi, sardine, anchovy, herring, bluefish, amberjack, marlin. Scombrotoxin fish poisoning, scombroid syndrome, scombroid, histamine fish poisoning, scombroid poisoning įlushed skin, headache, itchiness, blurred vision, abdominal cramps, diarrhea Įat fish high in histamine due to improper processing Medical condition Scombroid food poisoning
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